2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease NF-κB
  3. Glucocorticoid Receptor Reactive Oxygen Species NO Synthase
  4. Beclometasone dipropionate monohydrate

Beclometasone dipropionate monohydrate  (Synonyms: 丙酸倍氯米松一水合物)

目录号: HY-13571B
产品使用指南

摩尔计算器

Beclometasone dipropionate monohydrate 是 Beclometasone 的前体活性分子，是口服有效的糖皮质激素受体激动剂。Beclometasone dipropionate monohydrate 通过糖皮质激素受体发挥作用，抑制炎症和过度增殖。Beclometasone dipropionate monohydrate 可用于哮喘研究。

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Beclometasone dipropionate monohydrate Chemical Structure

Beclometasone dipropionate monohydrate Chemical Structure

CAS No. : 77011-63-3

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Beclometasone dipropionate monohydrate 的其他形式现货产品:

Customer Review

Other Forms of Beclometasone dipropionate monohydrate:

Beclometasone dipropionate monohydrate 相关抗体

Top Publications Citing Use of Products

查看 NO Synthase 亚型特异性产品:

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Beclometasone dipropionate monohydrate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma [1][2].

IC50 & Target

iNOS

 

体外研究
(In Vitro)

Beclometasone dipropionate monohydrate (1-100 nM; 20 min) inhibits STAT-1 expression and reduces the levels of iNOS, ROS and NT generated by rhIL-17A in 16HBE cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Beclometasone dipropionate monohydrate 相关抗体:

Western Blot Analysis[2]

Cell Line: 16HBE cells
Concentration: 1, 10 and 100 nM
Incubation Time: 20 min
Result: Reduced the levels of iNOS, ROS and NT generated by rhIL-17A.
体内研究
(In Vivo)

Beclometasone dipropionate monohydrate (150 µg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male BALB/c mice with asthma[1]
Dosage: 150 µg/kg
Administration: Nebulization
Result: Decreased total cell number and relative eosinophil number in BALF.
Clinical Trial
分子量

539.06

Formula

C28H39ClO8
CAS 号
中文名称

丙酸倍氯米松一水合物； 二丙酸倍氯米松一水合物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Beclometasone dipropionate monohydrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Beclometasone dipropionate77011-63-3丙酸倍氯米松一水合物 二丙酸倍氯米松一水合物Glucocorticoid ReceptorReactive Oxygen SpeciesNO SynthaseNitric oxide synthasesNOSSTAT-1iNOS16HBE cellsasthmainflammationInhibitorinhibitorinhibit

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