2. JAK/STAT Signaling Immunology/Inflammation Protein Tyrosine Kinase/RTK
  3. EGFR CD3
  4. BIHC

BIHC 是一种 Her2-CD3 双特异性抗体，由抗 Her2 的单域抗体和抗 CD3 的单链可变区片段 (Fv) 以类似 IgG 的格式构建而成。BIHC 具有有效的体内抗肿瘤活性，可以特异性地结合表达 Her2 的肿瘤细胞，并能通过募集 T 细胞高效杀死 Her2 阳性癌细胞，从而用于 Her2 阳性癌症的研究。

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BIHC Chemical Structure

BIHC Chemical Structure

CAS No. : 1642826-40-1

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     可免费申领三个不同产品的试用装。

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BIHC 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

查看所有亚型
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BIHC is a Her2-CD3 bispecific antibody constructed from a single-domain antibody targeting Her2 and a single-chain variable fragment (Fv) targeting CD3, formatted in an IgG-like structure. BIHC demonstrates effective antitumor activity in vivo, specifically binding to tumor cells expressing Her2 and efficiently eliminating Her2-positive cancer cells by recruiting T cells, thus being used in the study of Her2-positive cancers[1].

分子量

492.91

Formula

C26H21ClN2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BIHC 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIHC1642826-40-1EGFRCD3Epidermal growth factor receptorErbB-1HER1Cluster of differentiation 3Her2-positive cancersantitumor activitieInhibitorinhibitorinhibit

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目录号：
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