2. 多肽产品
  3. 多肽及其衍生物
  4. 抑制剂与底物肽
  5. BIM-23027

BIM-23027 是一种 sst2 受体的选择性激动剂 (EC50=0.32 nM)，与生长抑素 (SRIF, 一种环状十四肽) 具有相似的作用。BIM-23027 刺激多巴胺释放，并由 Glu 依赖机制介导。

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Custom Peptide Synthesis

BIM-23027 Chemical Structure

BIM-23027 Chemical Structure

CAS No. : 78981-49-4

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BIM-23027 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BIM-23027 is a selective agonist of sst2 receptor (EC50=0.32 nM), with similar effect to somatostatin (SRIF), a cyclic tetradecapeptide. BIM-23027 stimulates dopamine release, which is mediated by a Glu-dependent mechanism[1][2].

IC50 & Target

EC50: 0.32 nM (sst2)[2]
体外研究
(In Vitro)

BIM-23027 (10,50 和 100 nM; 90分钟) 显著增加多巴胺水平[1]。
BIM-23027 (50 nM; 100 nM SRIF 处理前 15 分钟孵育) 显著减弱了天然肽的作用[1]。
BIM-23027 (30 nM; 30 分钟) 卡威酚刺激的基底鳞状细胞增加 60-70%，EC50 为 0.29 nM[2]。
BIM-23027 与大鼠结肠粘膜 [125I]Tyr11-SRIF 结合位点的亚群相互作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BIM-23027 相关抗体:
分子量

794.94

Formula

C43H54N8O7
CAS 号
Sequence Shortening

Cyclo[{(NMe)Ala}-FWKTF]
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BIM-23027 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIM-2302778981-49-4BIM23027BIM 23027OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P3958
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