2. Anti-infection
  3. Enterovirus
  4. Brilliant Black BN

Brilliant Black BN  (Synonyms: E 151)

目录号: HY-128382 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Brilliant black BN (E151) 是一种偶氮染料 dye 和一种食品着色剂。Brilliant black BN (E151) 是一种很有前途的抗病毒试剂 (antiviral agent )，通过抑制 EV71 与其细胞脱衣因子亲环素a的相互作用来对抗 EV71 感染。Brilliant black BN (E151) 有潜力用于传染性疾病的相关研究。

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Brilliant Black BN Chemical Structure

Brilliant Black BN Chemical Structure

CAS No. : 2519-30-4

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥470
In-stock
5 mg ￥378
In-stock
10 mg ￥492
In-stock
25 mg ￥788
In-stock
50 mg ￥1220
In-stock
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Customer Review

Brilliant Black BN 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Brilliant black BN (E151) is an azo dye and a food colorant[1]. Brilliant black BN is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Brilliant black BN has the potential for the investigation of contagious disease[2].

IC50 & Target

IC50: 2.39 µM- 28.12 µM (various strains of EV71)[2]
体外研究
(In Vitro)

Brilliant black BN (E151) inhibits the interaction between EV71 and its cellular uncoating factor cyclophilin A [1].
Brilliant black BN (E151) inhibited the infection EV71 -GFP at a concentration of 300 μM as evidenced from the reduced GFP signals. Brilliant black BN (E151)exhibits the inhibition of EV71 -GFP as a dose-dependent manner in infected RD cells, exhibits an IC50 value of 10.1 μM[1].
Brilliant black BN (E151) is able to inhibit all tested 28 EV71, CVA16 and CVA6 strains. In rhabdomyosarcoma cells, 50% inhibitory concentration 29 of the dye E151 for various strains of EV71 ranged from 2.39 μM to 28.12 μM ,whereas its 50% cytotoxic concentration is 1870 μM [1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Brilliant Black BN 相关抗体:
体内研究
(In Vivo)

Brilliant black BN (E151)(intraperitoneal injection; 200 mg/kg; 14 days)exhibits mild illness with clinical scores less than 3 and subsequently recovered when compared with PBS-group.All E151 270 treated mice are completely protected throughout the experiment[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 14-days old AG129 mice with EV71[1]
Dosage: 200 mg/kg
Administration: Intraperitoneal injection
Result: Had a Protective eddect on EV71 challenged AG129 mice by dye E151.
分子量

867.68

Formula

C28H17N5Na4O14S4
CAS 号
性状

固体

颜色

Brown to black

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 125 mg/mL (144.06 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.1525 mL 5.7625 mL 11.5250 mL
5 mM 0.2305 mL 1.1525 mL 2.3050 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Brilliant Black BN 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1525 mL 5.7625 mL 11.5250 mL 28.8125 mL
5 mM 0.2305 mL 1.1525 mL 2.3050 mL 5.7625 mL
10 mM 0.1152 mL 0.5762 mL 1.1525 mL 2.8812 mL
15 mM 0.0768 mL 0.3842 mL 0.7683 mL 1.9208 mL
20 mM 0.0576 mL 0.2881 mL 0.5762 mL 1.4406 mL
25 mM 0.0461 mL 0.2305 mL 0.4610 mL 1.1525 mL
30 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.9604 mL
40 mM 0.0288 mL 0.1441 mL 0.2881 mL 0.7203 mL
50 mM 0.0230 mL 0.1152 mL 0.2305 mL 0.5762 mL
60 mM 0.0192 mL 0.0960 mL 0.1921 mL 0.4802 mL
80 mM 0.0144 mL 0.0720 mL 0.1441 mL 0.3602 mL
100 mM 0.0115 mL 0.0576 mL 0.1152 mL 0.2881 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Brilliant Black BN2519-30-4E 151E151E-151EnterovirusRhinovirusHRVHRVsHEVHEVsEV71,infectionHFMDantiviral,foodadditive,contagiousdiseaseInhibitorinhibitorinhibit

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目录号：
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