2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. Cabiralizumab

Cabiralizumab  (Synonyms: 卡比利珠单抗; FPA 008; Anti-Human CSF1R Recombinant Antibody)

目录号: HY-P99259 纯度: 99.59%
COA

摩尔计算器

Cabiralizumab (FPA 008) 是一种抗 CSF1R 单克隆抗体 (MAb)。Cabiralizumab 可增强 T 细胞浸润和抗肿瘤 T 细胞免疫反应。Cabiralizumab 抑制破骨细胞的活化并阻止骨质破坏，可用于类风湿性关节炎 (RA) 的研究。Cabiralizumab 可与 Nivolumab (HY-P9903) 结合用于肺癌研究。

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CAS No. : 1613144-80-1

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

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规格 价格 是否有货 数量
1 mg ￥2800
In-stock
5 mg ￥7200
In-stock
10 mg ￥11500
In-stock
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100 mg   询价  

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Customer Review

Cabiralizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cabiralizumab (FPA 008) is an anti-CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research[1][2].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Humanized
IC50 & Target

CSF1R[1]
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

卡比利珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Immobilized Human M-CSFR/CSF1R Protein can bind Cabiralizumab. The EC50 for this effect is 2.465 ng/mL.
纯度 & 产品资料
参考文献

Cabiralizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cabiralizumab1613144-80-1FPA 008 Anti-Human CSF1R Recombinant Antibody卡比利珠单抗FPA008FPA-008c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1RT cellarthritisRAlung cancerimmune responsetumorInhibitorinhibitorinhibit

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