2. Anti-infection
  3. Parasite
  4. Carbonic anhydrase inhibitor 27

Carbonic anhydrase inhibitor 27 (compund 5g) 是一种抗锥虫剂，可减少血流中的寄生虫，并提高感染小鼠的生存率。

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Carbonic anhydrase inhibitor 27 Chemical Structure

Carbonic anhydrase inhibitor 27 Chemical Structure

CAS No. : 167098-81-9

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Carbonic anhydrase inhibitor 27 相关抗体

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Carbonic anhydrase inhibitor 27 (compund 5g) is an antitrypanosomal agent that reduces parasites in the bloodstream and improves survival of infected mice[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Peritoneal macrophage cell CC50
64 μM
Compound: 5g
Cytotoxicity against BALB/c mouse peritoneal macrophages after 48 hrs by MTT/LDH assay
Cytotoxicity against BALB/c mouse peritoneal macrophages after 48 hrs by MTT/LDH assay
[PMID: 24299463]
Peritoneal macrophage cell CC50
92 μM
Compound: 5g
Cytotoxicity against BALB/c mouse peritoneal macrophages after 24 hrs by MTT/LDH assay
Cytotoxicity against BALB/c mouse peritoneal macrophages after 24 hrs by MTT/LDH assay
[PMID: 24299463]
THP-1 IC50
< 1 μM
Compound: 5g
Antitrypanosomal activity against Trypanosoma cruzi Y infected in human THP1 cells assessed as reduction of parasite burden after 48 hrs by Giemsa staining-based Neubauer chamber counting analysis
Antitrypanosomal activity against Trypanosoma cruzi Y infected in human THP1 cells assessed as reduction of parasite burden after 48 hrs by Giemsa staining-based Neubauer chamber counting analysis
[PMID: 24299463]
分子量

312.32

Formula

C17H16N2O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Carbonic anhydrase inhibitor 27 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Carbonic anhydrase inhibitor 27167098-81-9Carbonic anhydrase inhibitor27Carbonic anhydrase inhibitor-27ParasiteInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-12610
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