2. Immunology/Inflammation
  3. CD3
  4. Catumaxomab

Catumaxomab  (Synonyms: 卡妥索单抗)

目录号: HY-P9954 纯度: 98.56%
COA

摩尔计算器

Catumaxomab 是一种三功能 IgG2 抗体，由小鼠和大鼠的重链和轻链组成，与人 EpCAM 和人 CD3 受体结合。Catumaxomab Fc 端对 FcγR1 (CD 64) ，FcγRIIA (CD 32a) 和 FcγRIII (CD 16) 具有结合亲和力。Catumaxomab 可用于抗肿瘤 (尤其是上皮癌) 研究。

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CAS No. : 509077-98-9

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规格 价格 是否有货 数量
1 mg ￥4000
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Catumaxomab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers[1][2].

同型

IgG2a-kappa/G2b-lambda
种属

Mouse
体外研究
(In Vitro)

Catumaxomab (0-5 ng/mL; 3-7 天) 以剂量依赖的方式强烈抑制与 PBMC 共培养的 FaDu 肿瘤球体的生长[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Catumaxomab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2a-kappa/G2b-lambda
纯度 & 产品资料
参考文献

Catumaxomab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Catumaxomab509077-98-9CD3Cluster of differentiation 3Anti-cancerEpCAMIgG2 antibodymalignant ascitesepithelial cancersInhibitorinhibitorinhibit

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