2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. CBK289001

CBK289001 是一种抗酒石酸酸性磷酸酶 (TRAP/ACP5) 抑制剂。CBK289001 抑制 TRAP 5bMV，TRAP 5bOX 和 TRAP 5aOX，IC50 分别为 125 µM，4.21 µM 和 14.2 µM。

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CBK289001 Chemical Structure

CBK289001 Chemical Structure

CAS No. : 1212663-24-5

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CBK289001 相关抗体

Top Publications Citing Use of Products

查看 Protease Activated Receptor (PAR) 亚型特异性产品:

查看所有亚型
PAR1 PAR2 PAR4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively[1].

体外研究
(In Vitro)

Only CBK289001 inhibits TRAP3high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 µM or 100 µM[1].
CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CBK289001 相关抗体:
分子量

396.40

Formula

C19H20N6O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CBK289001 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CBK2890011212663-24-5CBK 289001CBK-289001Protease Activated Receptor (PAR)Thrombin receptorsTRAPACP5migrationanticancerInhibitorinhibitorinhibit

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产品名称：
CBK289001
目录号：
HY-124663
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