1. Immunology/Inflammation
  2. CD73
  3. CD73-IN-7

CD73-IN-7 是一种有效的 CD73 抑制剂。CD73 可以催化细胞外5'-磷酸腺苷 (5'-AMP) 产生腺苷,腺苷可以诱导免疫抑制作用,促进肿瘤增殖和/或转移。CD73-IN-7 用于制备治疗肿瘤相关疾病的药物 (摘自专利 WO2022052886A1,化合物 13)。

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CD73-IN-7 Chemical Structure

CD73-IN-7 Chemical Structure

CAS No. : 2763709-14-2

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  • 生物活性

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生物活性

CD73-IN-7 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-7 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 13)[1].

分子量

290.71

Formula

C13H11ClN4O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CD73-IN-7
目录号:
HY-147588
需求量: