2. Immunology/Inflammation
  3. COX
  4. Celecoxib (GMP Like)

Celecoxib (GMP Like)  (Synonyms: SC 58635 (GMP Like))

目录号: HY-14398GL
产品使用指南

摩尔计算器

Celecoxib (SC 58635) GMP Like 是 GMP 级别的 Celecoxib (HY-14398)。Celecoxib 是一种选择性的 COX-2 抑制剂，IC50 为 40 nM。

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Celecoxib (GMP Like) Chemical Structure

Celecoxib (GMP Like) Chemical Structure

CAS No. : 169590-42-5

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Celecoxib (GMP Like) 的其他形式现货产品:

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Other Forms of Celecoxib (GMP Like):

Celecoxib (GMP Like) 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 41 篇科研文献

WB

    Celecoxib (GMP Like) purchased from MCE. Usage Cited in: Br J Cancer. 2018 Jan;118(2):213-223.  [Abstract]

    Western blotting of EP2, EP4, COX-2, and PTEN using proteins extracted from SVHUC cells without MCA exposure and MCA-exposed SVHUC cells subsequently cultured for 6 weeks with ethanol or Celecoxib (1 mM). GAPDH served as a loading control.

    Celecoxib (GMP Like) purchased from MCE. Usage Cited in: Sci Rep. 2018 Mar 7;8(1):4108.  [Abstract]

    L02 cells exposed to PA (200 μM) with different concentrations of Celecoxib (Cel, 5-40 μM) for 24 h. Celecoxib decreases protein expression of COX-2 compared with control as indicated by western blot.

    Celecoxib (GMP Like) purchased from MCE. Usage Cited in: Oncol Rep. 2018 Oct;40(4):2242-2250.  [Abstract]

    Effects of Gefitinib(G) and Celecoxib(Cel) on ABCB1 (MDR1), FOXM1 and Bcl 2 protein levels in PC3/DR and DU145/DR cell lines. The effects of Gefitinib, Celecoxib and their combination on ABCB1 (MDR1), FOXM1 and Bcl 2 expression in the PC3/DR and DU145/DR cell lines are determined by a western blot assay.

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    COX COX-1 COX-2 COX-3

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Celecoxib (SC 58635) GMP Like is a GMP-class Celecoxib (HY-14398). Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM.

    IC50 & Target

    IC50: 40 nM (COX-2), 15 μM (COX-1)[1]
    分子量

    381.37

    Formula

    C17H14F3N3O2S
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Celecoxib (GMP Like) 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Celecoxib (GMP Like)169590-42-5SC 58635 (GMP Like)COXCyclooxygenaseInhibitorinhibitorinhibit

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    目录号：
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