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  3. Fungal
  4. Chitin synthase inhibitor 4

Chitin synthase inhibitor 4 

目录号: HY-150686 纯度: 99.48%
COA 产品使用指南

摩尔计算器

Chitin synthase inhibitor 4 (compound 4fh) 是一种几丁质酶 (CHS) 抑制剂，具有杀菌效果。Chitin synthase inhibitor 4 是一种潜在的基于 CHS 的农业杀菌剂。

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Chitin synthase inhibitor 4 Chemical Structure

Chitin synthase inhibitor 4 Chemical Structure

CAS No. : 2755847-31-3

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥1143
In-stock
1 mg ￥580
In-stock
5 mg ￥1500
In-stock
10 mg ￥2400
In-stock
25 mg ￥4300
In-stock
50 mg 现货 询价
100 mg 现货 询价
200 mg   询价  
500 mg   询价  

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Customer Review

Chitin synthase inhibitor 4 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase inhibitor with fungicidal effect. Chitin synthase inhibitor 4 is a potential chitin synthase-based fungicide in agriculture[1].

体外研究
(In Vitro)

Chitin synthase inhibitor 4 shows good antifungal activities against V. mali and S. sclerotiorum with EC50 values of 0.71 and 2.47 μg/mL, respectively[1].
Chitin synthase inhibitor 4 (50 μg/mL) displays potency inhibition against V. mali and S. sclerotiorum with inhibition rates of 90.3% and 88.7%, respectively[1].
Chitin synthase inhibitor 4 (1 μg/mL) blocks the hyphae growth, results abnormal growth, with inducing cell content decreasing, cell wall degradation, and plasmolysis[1].
Chitin synthase inhibitor 4 (50 μM; 3 h) exhibits inhibition against chitin synthase and polyoxin D with inhibition rates of 68.08% and 63.84%, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Chitin synthase inhibitor 4 相关抗体:
体内研究
(In Vivo)

Chitin synthase inhibitor 4 (50 μg/mL) has considerable curative and protective effects against S. sclerotiorum vivo, and no obvious phytotoxicity [1].
Chitin synthase inhibitor 4 has low acute toxicity, with no carcinogenic and mutagenic toxicity risk[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rat with Salmonella typhimurium[1]
Dosage: As Acute Oral Toxicity for Chemicals-Acute Toxic Class Method
Administration: Oral gavage
Result: Showed acute toxicity of 3.58 as toxicity grading standard, and negative carcinogenic toxicity, negative mutagenic toxicity.
分子量

346.36

Formula

C20H15FN4O
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (288.72 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.8872 mL 14.4358 mL 28.8717 mL
5 mM 0.5774 mL 2.8872 mL 5.7743 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Chitin synthase inhibitor 4 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8872 mL 14.4358 mL 28.8717 mL 72.1792 mL
5 mM 0.5774 mL 2.8872 mL 5.7743 mL 14.4358 mL
10 mM 0.2887 mL 1.4436 mL 2.8872 mL 7.2179 mL
15 mM 0.1925 mL 0.9624 mL 1.9248 mL 4.8119 mL
20 mM 0.1444 mL 0.7218 mL 1.4436 mL 3.6090 mL
25 mM 0.1155 mL 0.5774 mL 1.1549 mL 2.8872 mL
30 mM 0.0962 mL 0.4812 mL 0.9624 mL 2.4060 mL
40 mM 0.0722 mL 0.3609 mL 0.7218 mL 1.8045 mL
50 mM 0.0577 mL 0.2887 mL 0.5774 mL 1.4436 mL
60 mM 0.0481 mL 0.2406 mL 0.4812 mL 1.2030 mL
80 mM 0.0361 mL 0.1804 mL 0.3609 mL 0.9022 mL
100 mM 0.0289 mL 0.1444 mL 0.2887 mL 0.7218 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chitin synthase inhibitor 42755847-31-3Chitin synthase inhibitor4Chitin synthase inhibitor-4Fungalpyrimidine ether scaffold1,2,3,4-tetrahydroquinolineantifungal activityfungicidepolyoxin DSclerotinia sclerotiorumValsa maliInhibitorinhibitorinhibit

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