2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Chloropurine riboside

Chloropurine riboside  (Synonyms: 6-Chloropurine riboside)

目录号: HY-W007791 纯度: 99.93%
COA 产品使用指南

摩尔计算器

Chloropurine riboside 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。

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Chloropurine riboside Chemical Structure

Chloropurine riboside Chemical Structure

CAS No. : 5399-87-1

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Chloropurine riboside 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Huh-7 CC50
> 200 μM
Compound: 7
Cytotoxicity against Huh7 cells by XTT assay
Cytotoxicity against Huh7 cells by XTT assay
[PMID: 17766124]
Huh-7 EC50
31 μM
Compound: 7
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
[PMID: 17766124]
Vero IC50
48.7 μM
Compound: 1
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
[PMID: 17336519]
分子量

286.67

Formula

C10H11ClN4O4
CAS 号
性状

固体

颜色

Off-white to yellow

中文名称

6-氯-9-(β-D-呋喃核糖苷)嘌呤
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: 99.93%

COA (294 KB) HNMR (122 KB) RP-HPLC (250 KB)

产品使用指南 (1538 KB)
参考文献

Chloropurine riboside 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chloropurine riboside5399-87-16-Chloropurine riboside6-氯-9-(β-D-呋喃核糖苷)嘌呤Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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