2. Autophagy Metabolic Enzyme/Protease
  3. Autophagy FXR
  4. Cilofexor tromethamine

Cilofexor tromethamine  (Synonyms: GS-9674 tromethamine)

目录号: HY-109083A
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摩尔计算器

Cilofexor tromethamine (GS-9674 tromethamine)是一种非类固醇法尼烯氧化物受体激动剂，具有改善胆汁淤积和肝损伤标志物的活性。Cilofexor tromethamine在无肝硬化的患者中显示了良好的耐受性，并导致肝生化指标和胆汁淤积标志物的显著改善。Cilofexor tromethamine为处理原发性硬化性胆管炎提供了潜在的抑制选择。

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Cilofexor tromethamine Chemical Structure

Cilofexor tromethamine Chemical Structure

CAS No. : 2253764-93-9

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Cilofexor tromethamine 的其他形式现货产品:

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Cilofexor tromethamine 相关抗体

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  • 生物活性

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生物活性

Cilofexor tromethamine (GS-9674 tromethamine) is a nonsteroidal farnesene oxide receptor agonist with activity in improving markers of cholestasis and liver injury. Cilofexor tromethamine was shown to be well tolerated in patients without cirrhosis and resulted in significant improvements in liver biochemical parameters and cholestatic markers. Cilofexor tromethamine offers a potential inhibitory option for the management of primary sclerosing cholangitis[1].

分子量

707.99

Formula

C32H33Cl3N4O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cilofexor tromethamine 相关分类

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Keywords:

Cilofexor2253764-93-9GS-9674GS9674GS 9674AutophagyFXRNR1H4PSCnonsteroidalsafetyanti-inflammatoryantifibroticNASHoralInhibitorinhibitorinhibit

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