2. Apoptosis
  3. Apoptosis
  4. Cinnamic acid sodium

Cinnamic acid sodium  (Synonyms: 肉桂酸钠盐)

目录号: HY-130762
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Cinnamic acid sodium 是一种天然存在的，具有口服活性的低毒性芳香脂肪酸。Cinnamic acid sodium 具有神经保护和抗炎作用。

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Cinnamic acid sodium Chemical Structure

Cinnamic acid sodium Chemical Structure

CAS No. : 538-42-1

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Cinnamic acid sodium 的其他形式现货产品:

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Other Forms of Cinnamic acid sodium:

Cinnamic acid sodium 相关抗体

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  • 生物活性

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生物活性

Cinnamic acid sodium is a orally active naturally occurring aromatic fatty acid of low toxicity. Cinnamic acid sodium shows neuroprotective and anti-inflammatory effects[1][2][3].

体外研究
(In Vitro)

Cinnamic acid sodium (0.05, 0.4, 3.2 mM; 6, 12, 24 h) 在 24 小时时以 3.2 mM 浓度诱导 HT-144 细胞凋亡[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cinnamic acid sodium 相关抗体:

Apoptosis Analysis[3]

Cell Line: NGM, HT-144 cells
Concentration: 0.05, 0.4, 3.2 mM
Incubation Time: 6, 12, 24 h
Result: Induced apoptosis in HT-144 cells in 3.2 mM at 24 h, no effect apoptosis in NGM cells.
体内研究
(In Vivo)

Cinnamic acid sodium (100 mg/kg; gavage) 可激活 PPARα，保护多巴胺能神经元的丢失，恢复纹状体纤维和神经递质，并改善 MPTP 中毒小鼠的行为功能[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks, C57BL/6 mice (18 mg/kg MPTP-HCl, i.p.; at 2-h intervals for 4 times)[1]
Dosage: 100 mg/kg
Administration: Gavage; starting from 3 h after the last injection of MPTP
Result: Protected nigral TH levels, protected striatal innervation and neurotransmitters, restored locomotor deficit, increased the activation of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in primary mouse astrocytes, protected striatal TH via PPARα.
分子量

170.14

Formula

C9H7NaO2
CAS 号
中文名称

肉桂酸钠盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cinnamic acid sodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cinnamic acid538-42-1肉桂酸钠盐Apoptosisneurotransmittersanti-inflammatoryapoptosisHT-144 cellsorally activeInhibitorinhibitorinhibit

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