2. 多肽产品
  3. 多肽及其衍生物
  4. 抑制剂与底物肽
  5. CPI1

CPI1 是一种有效的且高特异性的多药耐药蛋白 1 (MRP1) 抑制剂。CPI1 对 MRP1 具有纳摩尔级的抑制活性 (Ki: 100 nM)，对 P-糖蛋白 (Pgp) 的抑制作用很小。CPI1 与 LTC4 竞争结合 MRP1 的同一位点，抑制 ATP 水解和底物转运。CPI1 可用于药物递送和癌症化疗耐药性的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

CPI1 Chemical Structure

CPI1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

CPI1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CPI1 is a potent and highly specific multidrug resistance protein 1 (MRP1) inhibitor. CPI1 inhibits MRP1 (Ki: 100 nM) with nanomolar potency but shows minimal inhibition of P-glycoprotein (Pgp). CPI1 and LTC4 compete to bind to the same site of MRP1, inhibiting ATP hydrolysis and substrate transport. CPI1 can be used to study drug delivery and chemotherapy resistance in cancer[1].

IC50 & Target

Ki: 100 nM (MRP1)[1]
分子量

2299.43

Formula

C111H131N23O30S
Sequence

Cyclo(Ac-{d-Tyr}-Phe-Trp-Gly-Asn-Leu-His-Trp-Tyr-Tyr-Glu-Gln-Phe-Asp-Ser-Thr-Cys)
Sequence Shortening

Cyclo(Ac-{d-Tyr}-FWGNLHWYYEQFDSTC)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CPI1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CPI1CPI 1CPI-1Inhibitorinhibitorinhibit

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