1. 天然产物
  2. 疾病研究领域 植物 萜类
  3. 葫芦科 癌症 三萜
  4. 甜瓜
  5. Cucurbitacin A

Cucurbitacin A  (Synonyms: 葫芦素A)

目录号: HY-N4175
产品使用指南

Cucurbitacin A 是可从 Cucumis melo 分离得到的三萜皂苷,具有抗癌活性。

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Cucurbitacin A Chemical Structure

Cucurbitacin A Chemical Structure

CAS No. : 6040-19-3

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cucurbitacin A, a triterpenoid that could be isolated from the Stems of Cucumis melo, shows anti-cancer activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
0.4 μM
Compound: 11
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
[PMID: 19348465]
Bel-7402 IC50
0.3 μM
Compound: 11
Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
[PMID: 19348465]
CHO IC50
55.2 μM
Compound: 4
Cytotoxicity against CHO cells by MTT assay
Cytotoxicity against CHO cells by MTT assay
[PMID: 30108825]
体外研究
(In Vitro)

Cucurbitacin A inhibits the proliferation of A549 and BEL-7402 cells with IC50 values of 0.4 and 0.3 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

574.70

Formula

C32H46O9

CAS 号
中文名称

葫芦素A

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-N4175
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