Cupressuflavone 

Cupressuflavone is a natural product that can be found in Cupressus macrocarpa. Cupressuflavone exhibits anti-inflammatory and antiulcerogenic activities. Cupressuflavone also show protective effects against CCl₄-induced hepato- and nephrotoxicity in mice^[1][2][3].

Cupressuflavone (40-160 mg/kg; p.o. once daily for 5 days) 在肝脏和肾脏组织中通过增强抗氧化防御状态、减少脂质过氧化和防止 CCl₄ 诱导的病理变化来对抗氧化应激^[1]。
Cupressuflavone (40-160 mg/kg; p.o.) 在40, 100, 160 mg/kg 剂量下分别抑制角叉菜胶诱导的炎症爪水肿 55%、60% 和 64%^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

538.46

C₃₀H₁₈O₁₀

3952-18-9

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Al-Sayed E, et, al. Protective role of Cupressuflavone from Cupressus macrocarpa against carbon tetrachloride-induced hepato- and nephrotoxicity in mice. Planta Med. 2014 Dec;80(18):1665-71.  [Content Brief]

  [2]. Al-Sayed E, et, al. Anti-inflammatory and analgesic activities of cupressuflavone from Cupressus macrocarpa: Impact on pro-inflammatory mediators. Drug Dev Res. 2018 Feb;79(1):22-28.  [Content Brief]

  [3]. Koriem KMM, et, al. Protective effect of Cupressus sempervirens extract against indomethacin-induced gastric ulcer in rats. Interdiscip Toxicol. 2015 Mar;8(1):25-34.  [Content Brief]