2. PROTAC Epigenetics
  3. Epigenetic Reader Domain PROTACs
  4. CW-3308

CW-3308 是一种口服有效的 PROTAC，靶向 BRD9。CW-3308 由 PROTAC 靶蛋白配体 Naphthyridin-Me-dimethoxybenzene-COOH (HY-159596)、Linker 3-Azaspiro[5.5]undecane-9-methanol (HY-159598)、E3 泛素连接酶配体 Thalidomide-methylpyrrolidine (HY-159597) 组成，其中 E3 泛素连接酶配体+Linker 的偶联物是 Thalidomide-pyrrolidine-C-azaspiro (HY-159599)。

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CW-3308 Chemical Structure

CW-3308 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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CW-3308 相关抗体

Top Publications Citing Use of Products

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

生物活性

CW-3308 is an orally effective PROTAC targeting BRD9. CW-3308 consists of PROTAC target protein ligand Naphthyridin-Me-dimethoxybenzene-COOH (HY-159596), Linker 3-Azaspiro[5.5]undecane-9-methanol (HY-159598), and E3 ubiquitin ligase ligand Thalidomide-methylpyrrolidine (HY-159597), of which the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-pyrrolidine-C-azaspiro (HY-159599)[1].

IC50 & Target

BRD9[1]
分子量

800.90

Formula

C45H48N6O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

CW-3308 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CW-3308CW3308CW 3308Epigenetic Reader DomainPROTACsInhibitorinhibitorinhibit

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产品名称：
CW-3308
目录号：
HY-159579
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