1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. CYP1B1-IN-5

CYP1B1-IN-5 (Compound 6q) 是一种有效的、选择性的细胞色素 P450 1B1 (CYP1B1) 抑制剂,IC50 为 4.7 nM。

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CYP1B1-IN-5 Chemical Structure

CYP1B1-IN-5 Chemical Structure

CAS No. : 176442-56-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CYP1B1-IN-5 (Compound 6q) is a potent and selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM[1].

IC50 & Target[1]

CYP1B1

4.7 nM (IC50)

CYP1A1

190.7 nM (IC50)

CYP1A2

585.7 nM (IC50)

体外研究
(In Vitro)

CYP1B1-IN-5 (Compound 6q) 通过与残基 Phe231、Phe134 和血红素形成 π-π 叠加相互作用,与 CYP1B1 的结合口袋结合[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

349.12

Formula

C14H8INO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CYP1B1-IN-5
目录号:
HY-152196
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