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  4. D595

D595是一种苯乙胺类钙通道阻滞剂，具有强效的负性肌力活性。D595在其对应的药理学研究中表现出明显的效能，特别是在抑制单胺神经递质的摄取方面。D595在与多巴胺转运体（DAT）、血清素转运体（SERT）和去甲肾上腺素转运体（NET）的结合中具有较高的亲和力。D595的结构调整尤其是对氢氧基立体化学的变化，显著影响了其与转运体的相互作用，显示出对立体异构体的特异性偏好。

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D595 Chemical Structure

D595 Chemical Structure

CAS No. : 16740-29-7

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D595 相关抗体

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  • 生物活性

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生物活性

D595 is a phenylethylamine calcium channel blocker with potent negative inotropic activity. D595 has shown significant efficacy in its corresponding pharmacological studies, especially in inhibiting the uptake of monoamine neurotransmitters. D595 has high affinity in binding to the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET). Structural adjustments of D595, especially changes in the hydroxyl stereochemistry, significantly affect its interaction with the transporters, showing a specific preference for stereoisomers[1].

分子量

463.44

Formula

C25H32Cl2N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

D595 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D59516740-29-7D 595D-595OthersInhibitorinhibitorinhibit

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