2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Dehydrodiconiferyl alcohol

Dehydrodiconiferyl alcohol 是一种雌激素受体 (estrogen receptor) 激动剂，可以促进 BMP-2 诱导的成骨细胞生成。Dehydrodiconiferyl alcohol 还通过灭活 NF-κB 通路发挥抗炎活性。

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Dehydrodiconiferyl alcohol Chemical Structure

Dehydrodiconiferyl alcohol Chemical Structure

CAS No. : 4263-87-0

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Other Forms of Dehydrodiconiferyl alcohol:

Dehydrodiconiferyl alcohol 相关抗体

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

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  • 参考文献

生物活性

Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Hep 3B2 IC50
65.5 μM
Compound: 2
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
[PMID: 29567344]
HepG2 IC50
78.6 μM
Compound: 2
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
[PMID: 29567344]
分子量

358.39

Formula

C20H22O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dehydrodiconiferyl alcohol 相关分类

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dehydrodiconiferyl alcohol4263-87-0Estrogen Receptor/ERRInhibitorinhibitorinhibit

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