2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Dicentrine hydrochloride

Dicentrine hydrochloride  (Synonyms: 荷苞牡丹碱盐酸盐)

目录号: HY-N6969A
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摩尔计算器

Dicentrine hydrochloride是一种具有抗炎和抗癌活性的药物。Dicentrine hydrochloride通过增强TNF-α诱导的A549肺腺癌细胞凋亡来发挥其作用。Dicentrine hydrochloride提高了caspase-8、-9、-3和聚（ADP-核糖）聚合酶（PARP）活性。Dicentrine hydrochloride抑制了TNF-α诱导的A549细胞的侵袭和迁移。Dicentrine hydrochloride显著抑制了TNF-α激活的TAK1、p38、JNK和Akt信号通路，降低了NF-κB和AP-1的转录活性。

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Dicentrine hydrochloride Chemical Structure

Dicentrine hydrochloride Chemical Structure

CAS No. : 5742-03-0

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Dicentrine hydrochloride 的其他形式现货产品:

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Dicentrine hydrochloride 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Dicentrine hydrochloride is a drug with anti-inflammatory and anti-cancer activity. Dicentrine hydrochloride exerts its effects by enhancing TNF-α-induced apoptosis in A549 lung adenocarcinoma cells. Dicentrine hydrochloride increases caspase-8, -9, -3 and poly(ADP-ribose) polymerase (PARP) activities. Dicentrine hydrochloride inhibits TNF-α-induced invasion and migration of A549 cells. Dicentrine hydrochloride significantly inhibited the TNF-α-activated TAK1, p38, JNK and Akt signaling pathways, and reduced the transcriptional activities of NF-κB and AP-1[1].

分子量

375.85

Formula

C20H22ClNO4
CAS 号
中文名称

荷苞牡丹碱盐酸盐
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dicentrine hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dicentrine5742-03-0荷苞牡丹碱盐酸盐Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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