2. PI3K/Akt/mTOR Metabolic Enzyme/Protease
  3. Akt Dihydrofolate reductase (DHFR) Endogenous Metabolite
  4. Diosbulbin C

Diosbulbin C 是一种二萜内酯成分，可从传统中药 Dioscorea bulbifera L. 中提取。Diosbulbin C 在非小细胞肺癌 (NSCLC) 中具有较高的抗癌活性。Diosbulbin C 可诱导 NSCLC 中的细胞周期停滞在 G0/G1 期。Diosbulbin C 还可能通过下调 AKT、DHFR 和 TYMS 的表达/活性来抑制 NSCLC 细胞的增殖。

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Diosbulbin C Chemical Structure

Diosbulbin C Chemical Structure

CAS No. : 20086-07-1

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Diosbulbin C 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC). Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS[1][1].

分子量

362.37

Formula

C19H22O7
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Diosbulbin C 相关分类

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Keywords:

Diosbulbin C20086-07-1AktDihydrofolate reductase (DHFR)Endogenous MetabolitePKBProtein kinase BInhibitorinhibitorinhibit

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