2. Immunology/Inflammation
  3. Complement System
  4. Eculizumab

Eculizumab  (Synonyms: 依库珠单抗; Anti-Human C5, Humanized Antibody)

目录号: HY-P9914 纯度: 97.81%
COA

摩尔计算器

Eculizumab (Anti-Human C5, Humanized Antibody) 是一种针对补体 C5 (complement C5) 的长效人源化单克隆抗体。Eculizumab 抑制 C5 裂解为 C5a 和 C5b，因此抑制末端补体系统的部署，包括膜攻击复合物 (MAC) 的形成。Eculizumab 具有用于溶血研究的潜力。

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CAS No. : 219685-50-4

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规格 价格 是否有货 数量
1 mg ￥2300
In-stock
5 mg ￥8500
In-stock
10 mg   询价  
50 mg   询价  

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Eculizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research[1].

同型

Human IgG1 kappa
推荐同型对照抗体
种属

Humanized
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

依库珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2-G4-kappa
纯度 & 产品资料
参考文献

Eculizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eculizumab219685-50-4Anti-Human C5, Humanized Antibody依库珠单抗Complement Systemhumanized monoclonal antibodycomplement C5C5aC5bmembrane attack complexMAChaemolysisInhibitorinhibitorinhibit

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