2. Inhibitory Antibodies
  3. Edrecolomab

Edrecolomab  (Synonyms: 依决洛单抗; Panorex; CO17-1A)

目录号: HY-P99231 纯度: 98.63%
COA

摩尔计算器

Edrecolomab (Panorex) 是一种针对细胞表面糖蛋白 17-1A 的小鼠单克隆抗体，在上皮组织和肿瘤上表达。Edrecolomab 显示出抗肿瘤活性，可用于结直肠癌的研究。

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CAS No. : 156586-89-9

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规格 价格 是否有货 数量
1 mg ￥2800
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5 mg ￥7000
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Edrecolomab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Edrecolomab (Panorex) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A, expressed on epithelial tissues and on various carcinomas. Edrecolomab shows anti-tumor activity and can be used in colorectal carcinoma research[1][2].

同型

Mouse IgG2a kappa
推荐同型对照抗体
种属

Mouse
体外研究
(In Vitro)

Edrecolomab (0-100 μg/mL; 20 h) shows moderate antibody-dependent cellular cytotoxicity (ADCC)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Edrecolomab 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: KATO III cells
Concentration: 0-100 μg/mL
Incubation Time: 20 hours
Result: Exhibited an ED50 value>100 ng/ml.
体内研究
(In Vivo)

Edrecolomab (intravenous injection; 30 μg/dose; day 1, 4 and 7 after tumor-cell inoculation) treatment inhibits tumor growth in the HT-29 nude mouse model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male nu/nu mice injected with HT-29 colon carcinoma cells[1]
Dosage: 30 μg/dose
Administration: Intravenous injection; 30 μg/dose; day 1, 4 and 7 after tumor-cell inoculation
Result: Inhibited tumor growth with a number of significant readings (p≤0.05).
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

依决洛单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2a-kappa
纯度 & 产品资料
参考文献

Edrecolomab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Edrecolomab156586-89-9Panorex CO17-1A依决洛单抗Othersglycoprotein 17-1Aanti-tumor activitycolorectal carcinomaKATO III cellInhibitorinhibitorinhibit

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