2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR-IN-28

EGFR-IN-28 是一种有效的 EGFR 抑制剂。EGFR-IN-28 具有抗肿瘤活性。

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EGFR-IN-28 Chemical Structure

EGFR-IN-28 Chemical Structure

CAS No. : 2754392-31-7

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EGFR-IN-28 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

查看所有亚型
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity[1].

IC50 & Target[1]

EGFR

 

体外研究
(In Vitro)

EGFR-IN-28 inhibits Δ19Del, L858R, Δ19Del/T790M, L858R/T790M, Δ19Del/T790M/C797S, L858R/T790M/C797S (all IC50s≤50nM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

EGFR-IN-28 相关抗体:
分子量

711.68

Formula

C31H39BrN10O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

EGFR-IN-28 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-282754392-31-7EGFREpidermal growth factor receptorErbB-1HER1Δ19DelL858RΔ19Del/T790ML858R/T790MΔ19Del/T790M/C797SL858R/T790M/C797SInhibitorinhibitorinhibit

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产品名称：
EGFR-IN-28
目录号：
HY-142681
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