2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR-IN-32

EGFR-IN-32 是一种有效的 EGFR 抑制剂。表皮生长因子受体 (EGFR) 的过度表达和突变已被清楚地证明会导致无法控制的细胞生长，并且与大多数癌症疾病，尤其是 NSCLC 的进展有关。EGFR-IN-32 具有研究 EGFR 突变相关疾病的潜力 (摘自专利 WO2021185297A1，化合物 2)。

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EGFR-IN-32 Chemical Structure

EGFR-IN-32 Chemical Structure

CAS No. : 2701553-78-6

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EGFR-IN-32 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EGFR-IN-32 is a potent inhibitor of EGFR. Overexpression and mutation of the epidermal growth factor receptor (EGFR) has been clearly demonstrated to lead to uncontrollable cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-32 has the potential for the research of diseases associated with EGFR mutations (extracted from patent WO2021185297A1, compound 2)[1].

分子量

538.64

Formula

C31H34N6O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

EGFR-IN-32 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-322701553-78-6EGFREpidermal growth factor receptorErbB-1HER1uncontrollable cell growthNSCLCEGFR mutationInhibitorinhibitorinhibit

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目录号：
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