1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  2. EGFR
  3. EGFR-TK-IN-3

EGFR-TK-IN-3 (3) 是 EGFR 的抑制剂,其对 Erlotinib (HY-50896) 耐药的 A549 细胞的 IC50 值为 2.33 μM。

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EGFR-TK-IN-3 Chemical Structure

EGFR-TK-IN-3 Chemical Structure

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     可免费申领三个不同产品的试用装。

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EGFR-TK-IN-3 (3) is an EGFR TK inhibitor, with an IC50 of 2.33 μM against Erlotinib (HY-50896)-resistant A549 cells[1].

体外研究
(In Vitro)

该化合物的抗癌作用机制涉及EGFR TK抑制活性和肺癌细胞产生活性氧的能力的结合[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

722.65

Formula

C38H46FeN6O5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
EGFR-TK-IN-3
目录号:
HY-163860
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