Elinogrel potassium  (Synonyms: PRT060128 potassium)

Elinogrel (PRT060128) potassium is a reversible, competitive and orally active P2Y₁₂ antagonist. Elinogrel potassium inhibits thrombosis^[1][2].

Elinogrel (60 mg/kg; p.o.; daily for 3 days) 可抑制血栓形成^[2]。
Elinogrel (1 mg/kg; i.v.) 可阻断在 FeCl3 (HY-Y0266) 诱发的血管损伤模型中经氯吡格雷 (HY-15283) (50 mg/kg p.o., 3 days) 治疗的小鼠中阻断残留血栓形成^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

563.04

C₂₀H₁₅ClFKN₅O₅S₂

936501-01-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Ueno M, et al. Elinogrel: pharmacological principles, preclinical and early phase clinical testing. Future Cardiol. 2010 Jul;6(4):445-53.  [Content Brief]

  [2]. Haberstock-Debic H, et al. A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist. J Pharmacol Exp Ther. 2011 Oct;339(1):54-61.  [Content Brief]