2. Anti-infection
  3. Parasite
  4. Eugenitin

Eugenitin 是一种聚酮化合物，能从南美药用植物的相关真菌 Mycoleptodiscus indicus 中分离得到。Eugenitin 抑制大利士曼原虫 (Leishmania major)，LD50=39.9 μM。Eugenitin 对几种人癌细胞系的细胞毒性低 (IC50 >131 μM)。

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Eugenitin Chemical Structure

Eugenitin Chemical Structure

CAS No. : 480-12-6

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Eugenitin 相关抗体

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1].

IC50 & Target

LD50: 39.9 μM (Leishmania major)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-8 IC50
> 113 μM
Compound: 3
Cytotoxicity against human HCT8 cells by colorimetric method
Cytotoxicity against human HCT8 cells by colorimetric method
[PMID: 24387625]
HL-60 IC50
> 113 μM
Compound: 3
Cytotoxicity against human HL60 cells by colorimetric method
Cytotoxicity against human HL60 cells by colorimetric method
[PMID: 24387625]
Lymphocyte IC50
> 113 μM
Compound: 3
Cytotoxicity against human lymphocytes by colorimetric method
Cytotoxicity against human lymphocytes by colorimetric method
[PMID: 24387625]
MDA-MB-435 IC50
> 113 μM
Compound: 3
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
[PMID: 24387625]
PC-3 IC50
> 113 μM
Compound: 3
Cytotoxicity against human PC3 cells by colorimetric method
Cytotoxicity against human PC3 cells by colorimetric method
[PMID: 24387625]
SF-295 IC50
> 113 μM
Compound: 3
Cytotoxicity against human SF295 cells by colorimetric method
Cytotoxicity against human SF295 cells by colorimetric method
[PMID: 24387625]
分子量

220.22

Formula

C12H12O4
CAS 号
结构分类
初始来源

Mycoleptodiscus indicus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Eugenitin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eugenitin480-12-6ParasiteLeishmania majorMycoleptodiscus indicusInhibitorinhibitorinhibit

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