2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Cytotoxin Topoisomerase
  4. Exatecan Intermediate 4

Exatecan Intermediate 4 (compound B) 是 Exatecan (DX-8951, HY-13631) 中间体。Exatecan 是一种抗癌剂，属于喜树碱类似物。它通过与 DNA 发生相互作用来干扰肿瘤细胞的增殖和分裂，从而抑制肿瘤的生长。Exatecan 主要用于卵巢癌、肺癌和乳腺癌等多种癌症的研究。

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Exatecan Intermediate 4 Chemical Structure

Exatecan Intermediate 4 Chemical Structure

CAS No. : 2436720-50-0

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规格 价格 是否有货 数量
5 mg ￥230
In-stock
10 mg ￥320
In-stock
25 mg ￥520
In-stock
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100 mg   询价  

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Other Forms of Exatecan Intermediate 4:

Exatecan Intermediate 4 相关抗体

Top Publications Citing Use of Products

查看 ADC Cytotoxin 亚型特异性产品:

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Auristatin Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

生物活性

Exatecan Intermediate 4 (compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1][2].

IC50 & Target

Camptothecins

 

分子量

244.69

Formula

C11H14ClFN2O
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料

Exatecan Intermediate 4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Exatecan Intermediate 42436720-50-0Exatecan Intermediate4Exatecan Intermediate-4ADC CytotoxinTopoisomeraseADC PayloadInhibitorinhibitorinhibit

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目录号：
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