2. Immunology/Inflammation
  3. CD3
  4. Forimtamig

Forimtamig  (Synonyms: RG-6324; RO-7425781)

目录号: HY-P991055
技术支持

Forimtamig (RG-6324) 是一种 GPRC5DxCD3 T 细胞结合双特异性抗体。Forimtamig 具有 2 + 1 结构，包含两个高亲和力 GPRC5D 结合部分和一个 CD3 结合剂。Forimtamig 还具有 P329G LALA 突变 Fc 结构域，可抑制 Fcγ 受体和 C1q 结合，但仍保留与 Fc 受体的结合。Forimtamig 的同种型对照可以参考人 IgG1 kappa，同种型对照 (HY-P99001)。

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Forimtamig Chemical Structure

Forimtamig Chemical Structure

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Forimtamig 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001)[1].

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Forimtamig 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ForimtamigRG-6324 RO-7425781RG6324RG 6324RO7425781RO 7425781RO-7425781CD3Cluster of differentiation 3GPRC5DxCD3 T-cell-engaging bispecific antibodyInhibitorinhibitorinhibit

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