2. Anti-infection Cell Cycle/DNA Damage
  3. HIV Nucleoside Antimetabolite/Analog Antibiotic
  4. Formycin A

Formycin A  (Synonyms: NSC 102811)

目录号: HY-102026 纯度: ≥99.0%
COA 产品使用指南 技术支持

Formycin A (NSC 102811) 是一种嘌呤核苷抗生素，一种有效的人类免疫缺陷病毒 1 型 (HIV-1) 的抑制剂，EC50 为 10 μM。Formycin A 显示抗肿瘤和抗病毒活性。

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Formycin A Chemical Structure

Formycin A Chemical Structure

CAS No. : 6742-12-7

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1 mg ￥2600
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Other Forms of Formycin A:

Formycin A 相关抗体

Top Publications Citing Use of Products

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HIV HIV-1 HIV-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities[1][2].

IC50 & Target[1]

HIV-1

10 μM (EC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
L1210 IC50
1 μM
Compound: formycin A
Cytotoxic concentration required to reduce rate of L1210 cell proliferation after 48 hr
Cytotoxic concentration required to reduce rate of L1210 cell proliferation after 48 hr
[PMID: 4068000]
MDCK CC50
2.6 μM
Compound: 7; FMA
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay
[PMID: 35092894]
体外研究
(In Vitro)

Formycin A (NSC 102811; 1 μM, 5 μM, 10 μM) antagonizes Zidovudine (AZT; a dideoxynucleoside chain terminator).

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Formycin A 相关抗体:
分子量

267.24

Formula

C10H13N5O4
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

COA (172 KB)

产品使用指南 (1538 KB)
参考文献

Formycin A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Formycin A6742-12-7NSC 102811NSC102811NSC-102811HIVNucleoside Antimetabolite/AnalogAntibioticHuman immunodeficiency viruspurinenucleosideantibioticHumanimmunodeficiencyvirustypeHIV-1Inhibitorinhibitorinhibit

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目录号：
HY-102026
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