2. Anti-infection
  3. Dengue Virus Flavivirus
  4. FX-06

FX-06  (Synonyms: Fibrin-derived peptide Bβ15-42)

目录号: HY-106275 纯度: 99.98%
COA 产品使用指南 技术支持

FX-06 (Fibrin-derived peptide Bβ15-42) 是一种纤维蛋白 Bbeta 链衍生肽。FX-06 与 VE-cadherin 结合并抑制白细胞迁移，从而启动 VE-cadherin 介导的信号传导。FX-06 可用于缺血/再灌注损伤、登革休克综合征 (DSS) 的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

FX-06 Chemical Structure

FX-06 Chemical Structure

CAS No. : 88650-17-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥650
In-stock
5 mg ￥1600
In-stock
10 mg ￥2500
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

FX-06 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS)[1][2][4].

体外研究
(In Vitro)

FX-06 (50 μM, 3 days) inhibits the production of D2HG in HEK-293T cells transfected with IDH1 R132H[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

FX-06 相关抗体:
体内研究
(In Vivo)

FX06 (2.4 mg/kg, i.v. bolus) shows significantly improved pulmonary and circulatory function in a pig model of hemorrhagic shock and reperfusion[3].
FX06 (2.4 mg/kg, i.p., twice daily) improves survival and reduces capillary leak in mice with Dengue-induced shock[4].
FX06 (3.6 mg/kg, i.v.) protects mice from Ischemia/reperfusion (I/R)-induced kidney injury by aiding in epithelial cell proliferation and tissue repair[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Pig model of hemorrhagic shock and reperfusion [3]
Dosage: 2.4 mg/kg
Administration: Intravenous injection (i.v.) bolus
Result: Reduced raccumulation of myeloperoxidase-pos. cells (mainly neutrophils) in myocardium, liver, and small intestine, and reduced interleukin-6 plasma levels.
Animal Model: Mice with Dengue-induced shock[4]
Dosage: 2.4 mg/kg
Administration: Intraperitoneal injection (i.p.)
Result: Significantly improved survival rates, reduced capillary leak within lungs and the intestine, and reduced hemoconcentration and fibrinogen consumption.
Clinical Trial
分子量

3039.41

Formula

C133H216N44O38
CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

GHRPLDKKREEAPSLRPAPPPISGGGYR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (32.90 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.3290 mL 1.6451 mL 3.2901 mL
5 mM 0.0658 mL 0.3290 mL 0.6580 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

FX-06 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3290 mL 1.6451 mL 3.2901 mL 8.2253 mL
5 mM 0.0658 mL 0.3290 mL 0.6580 mL 1.6451 mL
10 mM 0.0329 mL 0.1645 mL 0.3290 mL 0.8225 mL
15 mM 0.0219 mL 0.1097 mL 0.2193 mL 0.5484 mL
20 mM 0.0165 mL 0.0823 mL 0.1645 mL 0.4113 mL
25 mM 0.0132 mL 0.0658 mL 0.1316 mL 0.3290 mL
30 mM 0.0110 mL 0.0548 mL 0.1097 mL 0.2742 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FX-0688650-17-3Fibrin-derived peptide Bβ15-42FX06FX 06Dengue VirusFlavivirusDENVD2HGHEK-293TischemiareperfusionDSSVE-cadherinInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
FX-06
目录号：
HY-106275
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z