2. Anti-infection
  3. SARS-CoV
  4. Gallinamide A

Gallinamide A 是一种组织蛋白酶L的有效抑制剂，其 IC50 值为 17.6 pM。

该游离形式化合物不稳定，推荐具有相同生物学活性的稳定盐形式 Gallinamide A TFA。

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Gallinamide A Chemical Structure

Gallinamide A Chemical Structure

CAS No. : 1208232-55-6

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Other Forms of Gallinamide A:

Gallinamide A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gallinamide A is a potent inhibitor of cathepsin L with an IC50 value of 17.6 pM.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
4T1 IC50
34.6 μM
Compound: 1
Antiproliferative activity against mouse 4T1 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse 4T1 cells after 48 hrs by MTT assay
[PMID: 30006166]
A-375 IC50
45.6 μM
Compound: 1
Antiproliferative activity against human A375 cells after 48 hrs by MTT assay
Antiproliferative activity against human A375 cells after 48 hrs by MTT assay
[PMID: 30006166]
A549 IC50
40.4 μM
Compound: 1
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
[PMID: 30006166]
B16-F10 IC50
59.7 μM
Compound: 1
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
[PMID: 30006166]
MCF7 IC50
45.5 μM
Compound: 1
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 30006166]
MDA-MB-231 IC50
34.9 μM
Compound: 1
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
[PMID: 30006166]
PANC-1 IC50
31.2 μM
Compound: 1
Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
[PMID: 30006166]
Vero C1008 CC50
> 100 μM
Compound: 1; GalA
Cytotoxicity against cells African green monkey Vero E6 cells incubated for 24 to 72 hrs by alamar blue assay
Cytotoxicity against cells African green monkey Vero E6 cells incubated for 24 to 72 hrs by alamar blue assay
[PMID: 34730959]
分子量

592.77

Formula

C31H52N4O7
CAS 号
结构分类
初始来源

marine cyanobacterium?Schizothrix?sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Gallinamide A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gallinamide A1208232-55-6SARS-CoVSARS coronavirusInhibitorinhibitorinhibit

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产品名称：
Gallinamide A
目录号：
HY-N10109
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