2. 天然产物
  3. 萜类 微生物
  4. 三萜
  5. Ganoderiol F

Ganoderiol F 是一种四环三萜，从 Ganoderma amboinense 中分离得到，被发现可诱导癌细胞系衰老。

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Ganoderiol F Chemical Structure

Ganoderiol F Chemical Structure

CAS No. : 114567-47-4

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规格 价格 是否有货 数量
1 mg ￥1400
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Ganoderiol F 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
5 μM
Compound: 14
Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay
Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay
[PMID: 22014750]
HepG2 IC50
20.7 μM
Compound: 2
Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24974349]
K562 IC50
54.9 μM
Compound: 22
Cytotoxicity against human K562 cells by MTT method
Cytotoxicity against human K562 cells by MTT method
[PMID: 26287401]
PC-3 IC50
79.5 μM
Compound: 22
Cytotoxicity against human PC3 cells by MTT method
Cytotoxicity against human PC3 cells by MTT method
[PMID: 26287401]
RAW264.7 IC50
36 μM
Compound: 7
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method
[PMID: 23357630]
分子量

454.68

Formula

C30H46O3
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源

Ganoderma amboinense
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Ganoderiol F 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderiol F114567-47-4OthersInhibitorinhibitorinhibit

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目录号：
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