1. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Cell Cycle/DNA Damage Others
  2. Cytochrome P450 PPAR Isotope-Labeled Compounds
  3. Gemfibrozil-d6-1

Gemfibrozil-d6-1  (Synonyms: CI-719-d6-1)

目录号: HY-B0258S1
产品使用指南

Gemfibrozil-d6-1 (CI-719-d6-1) 是氚代标记的 Gemfibrozil (HY-B0258)。Gemfibrozil 是一种 PPAR-α 激活剂,为一种降脂剂;Gemfibrozil 同时是 P450 的非选择性抑制剂,对 CYP2C9,2C19,2C8 和 1A2 的 Ki 值分别为 5.8,24,69 和 82 μM。

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Gemfibrozil-d<sub>6</sub>-1 Chemical Structure

Gemfibrozil-d6-1 Chemical Structure

CAS No. : 1160569-36-7

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Other Forms of Gemfibrozil-d6-1:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gemfibrozil-d6-1 (CI-719-d6-1) is the deuterium labeled Gemfibrozil (HY-B0258). Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively[1].

分子量

256.37

Formula

C15H16D6O3

CAS 号
非标记 CAS

25812-30-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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