2. Antibody-drug Conjugate/ADC Related
  3. ADC Antibody
  4. Gemtuzumab

Gemtuzumab  (Synonyms: 吉妥珠单抗)

目录号: HY-P99971 纯度: 98.04%
COA

摩尔计算器

Gemtuzumab 是一种靶向 CD33 抗原的 IgG4-κ 单克隆抗体，该抗原存在于急性髓系白血病 (AML) 的白血病成髓细胞上。Gemtuzumab 可用于合成一种抗体偶联药物 (ADC)，Gemtuzumab ozogamicin (HY-109539)。Gemtuzumab ozogamicin 由加利车霉素 (一种细胞毒性抗生素) 的细胞毒性衍生物和单克隆抗体组成。 Gemtuzumab ozogamicin 可用于急性髓性白血病的研究。

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规格 价格 是否有货 数量
1 mg ￥3400
In-stock
5 mg ￥8400
In-stock
10 mg   询价  
50 mg   询价  

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Gemtuzumab 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia[1][2].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Humanized
Clinical Trial
性状

液体

颜色

Colorless to light yellow

中文名称

吉妥珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Immobilized Siglec-3/CD33 Protein, Human can bind Gemtuzumab. The EC50 for this effect is 4.328 ng/mL.
纯度 & 产品资料

纯度: 98.04%

COA (264 KB) SEC-HPLC (219 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Gemtuzumab 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gemtuzumab吉妥珠单抗ADC Antibodyantibody-drug conjugateacute myeloid leukemiaAMLInhibitorinhibitorinhibit

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