2. Gene
  3. ADORA3 - adenosine A3 receptor Gene

ADORA3 - adenosine A3 receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：腺苷 A3 受体

种属: Rattus norvegicus

同用名: A3; TGPCR1

基因 ID: 100911796 | 基因类型: protein coding

关于 ADORA3

Primary_assembly 2: 193,388,713-193,392,357 forward strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 272 orthologues, 3 paralogues and is associated with 3 phenotypes.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联腺苷受体活性。参与G蛋白偶联受体信号通路；去甲肾上腺素分泌的调节；和突触小泡胞吐的调节。位于突触前膜。活跃于 Schaffer 侧支 - CA1 突触。与人类 ADORA3（腺苷 A3 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled Adenosine Receptor activity. Involved in G protein-coupled receptor signaling pathway; regulation of norepinephrine secretion; and regulation of synaptic vesicle exocytosis. Located in presynaptic membrane. Is active in Schaffer collateral - CA1 synapse. Orthologous to human ADORA3 (adenosine A3 receptor). [provided by Alliance of Genome Resources, Apr 2022]

ADORA3 基因产物(2)

mRNA Protein Name
NM_001302750.1 NP_001289679.1 adenosine receptor A3 isoform a
NM_001302751.1 NP_001289680.1 adenosine receptor A3 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled adenosine receptor activity IDA
IDA: 通过直接分析推断
1323836 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
12475223 RGD
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
8987783 RGD
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
8987783 RGD
involved in regulation of norepinephrine secretion IMP
IMP: 通过突变表型推断
16539684 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse EXP
EXP: 通过实验结果推断
8987783 RGD
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
8987783 RGD
located in presynaptic membrane IDA
IDA: 通过直接分析推断
14502093 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ADORA3 蛋白结构

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (14 - 311)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (15 - 41)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (48 - 75)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (84 - 114)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (145 - 163)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (192 - 222)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (241 - 271)

7tmA_Adenosine_R_A3

7tmA_Adenosine_R_A3: cd15070 (279 - 304)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
蛋白主名 其他名称

adenosine receptor A3

adenosine receptor A3-like

putative G-protein coupled receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00400 ADORA3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00401 Adora3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00402 ADORA3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ADORA3 NCBI NCBI:140
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