KCNMB2 - potassium calcium-activated channel subfamily M regulatory beta subunit 2 Gene

中文名称：钾钙激活通道亚家族 M 调节 β 亚基 2

种属: Homo sapiens

关于 KCNMB2

功能概要

MaxiK 通道是大电导、电压和钙敏感的钾通道，它们是控制平滑肌张力和神经元兴奋性的基础。 MaxiK 通道可由 2 个亚基形成：成孔 α 亚基和调节性 β 亚基。由该基因编码的蛋白质是一个辅助 β 亚基，可减少 MaxiK α 亚基电流的激活时间。可变剪接导致该基因的多个转录变体。文献中讨论了其他变体，但尚未描述其全长性质。[RefSeq 提供，2013 年 7 月]

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]