1. Gene
  2. Ano10 - anoctamin 10 Gene

Ano10 - anoctamin 10 Gene

种属: Mus musculus

同用名: Tmem16k

基因 ID: 102566 | 基因类型: protein coding

关于 Ano10

功能概要

This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to inhibit anion conductance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Dec 2012]

Ano10 基因产物(2)

mRNA Protein Name
NM_001271873.1 NP_001258802.1 anoctamin-10 isoform 2
NM_133979.3 NP_598740.1 anoctamin-10 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: 通过直接分析推断
23532839 MGI
NOT enables phospholipid scramblase activity IDA
IDA: 通过直接分析推断
23532839 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
20056604 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
20056604 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

anoctamin-10

transmembrane protein 16K

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ano10 NCBI NCBI:55129