2. Gene
  3. N4BP2L2 - NEDD4 binding protein 2 like 2 Gene

N4BP2L2 - NEDD4 binding protein 2 like 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：NEDD4 结合蛋白 2 like 2

种属: Homo sapiens

同用名: CG005; CG016; PFAAP5; 92M18.3

基因 ID: 10443 | 基因类型: protein coding

关于 N4BP2L2

Cytogenetic location: 13q13.1 Genomic coordinates (GRCh38): 13:32,432,485-32,538,868 (from NCBI)

This gene has 45 transcripts (splice variants), 175 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 5.4), ovary (RPKM 5.3) and 25 other tissues.

功能概要

启用酶结合活性。参与造血干细胞分化的负调控和造血干细胞增殖的正调控。位于核内。转录抑制复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables Enzyme binding activity. Involved in negative regulation of hematopoietic stem cell differentiation and positive regulation of hematopoietic stem cell proliferation. Located in nucleus. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2022]

N4BP2L2 基因产物(39)

mRNA Protein Name
NM_001278432.2 NP_001265361.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001320836.3 NP_001307765.1 NEDD4-binding protein 2-like 2 isoform 4
NM_001387001.1 NP_001373930.1 NEDD4-binding protein 2-like 2 isoform 4
NM_001387002.1 NP_001373931.1 NEDD4-binding protein 2-like 2 isoform 4
NM_001387004.1 NP_001373933.1 NEDD4-binding protein 2-like 2 isoform 5
NM_001387005.1 NP_001373934.1 NEDD4-binding protein 2-like 2 isoform 6
NM_001387006.1 NP_001373935.1 NEDD4-binding protein 2-like 2 isoform 6
NM_001387008.1 NP_001373937.1 NEDD4-binding protein 2-like 2 isoform 7
NM_001387009.1 NP_001373938.1 NEDD4-binding protein 2-like 2 isoform 7
NM_001387015.1 NP_001373944.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001387016.1 NP_001373945.1 NEDD4-binding protein 2-like 2 isoform 9
NM_001387017.1 NP_001373946.1 NEDD4-binding protein 2-like 2 isoform 5
NM_001387018.1 NP_001373947.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001387019.1 NP_001373948.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001387020.1 NP_001373949.1 NEDD4-binding protein 2-like 2 isoform 8
NM_001387059.1 NP_001373988.1 NEDD4-binding protein 2-like 2 isoform 19
NM_001387060.1 NP_001373989.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387079.1 NP_001374008.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387080.1 NP_001374009.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387081.1 NP_001374010.1 NEDD4-binding protein 2-like 2 isoform 15
NM_001387082.1 NP_001374011.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387083.1 NP_001374012.1 NEDD4-binding protein 2-like 2 isoform 16
NM_001387099.1 NP_001374028.1 NEDD4-binding protein 2-like 2 isoform 20
NM_001387100.1 NP_001374029.1 NEDD4-binding protein 2-like 2 isoform 17
NM_001387101.1 NP_001374030.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387102.1 NP_001374031.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387103.1 NP_001374032.1 NEDD4-binding protein 2-like 2 isoform 10
NM_001387104.1 NP_001374033.1 NEDD4-binding protein 2-like 2 isoform 11
NM_001387105.1 NP_001374034.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387106.1 NP_001374035.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387107.1 NP_001374036.1 NEDD4-binding protein 2-like 2 isoform 13
NM_001387108.1 NP_001374037.1 NEDD4-binding protein 2-like 2 isoform 13
NM_001387165.1 NP_001374094.1 NEDD4-binding protein 2-like 2 isoform 18
NM_001387223.1 NP_001374152.1 NEDD4-binding protein 2-like 2 isoform 16
NM_001387224.1 NP_001374153.1 NEDD4-binding protein 2-like 2 isoform 15
NM_001387225.1 NP_001374154.1 NEDD4-binding protein 2-like 2 isoform 14
NM_001395224.1 NP_001382153.1 NEDD4-binding protein 2-like 2 isoform 21
NM_014887.3 NP_055702.1 NEDD4-binding protein 2-like 2 isoform 2
NM_033111.5 NP_149102.3 NEDD4-binding protein 2-like 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
19506020 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
19506020 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of hematopoietic stem cell differentiation IMP
IMP: 通过突变表型推断
19506020 GOA
involved in positive regulation of hematopoietic stem cell proliferation IMP
IMP: 通过突变表型推断
19506020 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19506020 GOA
part of transcription repressor complex IDA
IDA: 通过直接分析推断
19506020 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

N4BP2L2 蛋白结构

AAA_33

AAA_33: AAA domain (404 - 536)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 583 a.a.
蛋白主名 其他名称

NEDD4-binding protein 2-like 2

phosphonoformate immuno-associated protein 5

N4BP2L2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
N4BP2L2 Q92802 PPIH Homo sapiens O43447
Y2H Array
25416956
种属内
N4BP2L2 Q92802 PPIL1 Homo sapiens Q9Y3C6
Validated Y2H
32296183
种属内
N4BP2L2 Q92802 HOXA1 Homo sapiens P49639
Validated Y2H
25416956
种属内
N4BP2L2 Q92802 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
25416956
种属内
N4BP2L2 Q92802 NAA38 Homo sapiens Q9BRA0
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08982 N4BP2L2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus N4BP2L2 MGD MGI:2687207
Macaca mulatta N4BP2L2 VGNC VGNC:75031
Canis familiaris N4BP2L2 VGNC VGNC:59086
Rattus norvegicus N4BP2L2 RGD RGD:1359603
Bos taurus N4BP2L2 VGNC VGNC:53827
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z