2. Gene
  3. HTATIP2 - HIV-1 Tat interactive protein 2 Gene

HTATIP2 - HIV-1 Tat interactive protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：HIV-1 Tat 相互作用蛋白 2

种属: Homo sapiens

同用名: CC3; TIP30; SDR44U1

基因 ID: 10553 | 基因类型: protein coding

关于 HTATIP2

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:20,363,714-20,383,782 (from NCBI)

This gene has 9 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in duodenum (RPKM 33.4), small intestine (RPKM 30.9) and 24 other tissues.

功能概要

启用蛋白质丝氨酸/苏氨酸激酶活性。参与输入细胞核和调节血管生成。在程序性细胞死亡的正调节上游或正调节内起作用； RNA 聚合酶 II 对转录的正调控；和蛋白质自身磷酸化。位于胞质溶胶和核膜中。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activity. Involved in import into nucleus and regulation of angiogenesis. Acts upstream of or within positive regulation of programmed cell death; positive regulation of transcription by RNA polymerase II; and protein autophosphorylation. Located in cytosol and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]

HTATIP2 基因产物(5)

mRNA Protein Name
NM_001098520.2 NP_001091990.1 oxidoreductase HTATIP2 isoform a precursor
NM_001098521.2 NP_001091991.1 oxidoreductase HTATIP2 isoform b
NM_001098522.2 NP_001091992.1 oxidoreductase HTATIP2 isoform b
NM_001098523.2 NP_001091993.1 oxidoreductase HTATIP2 isoform c
NM_006410.5 NP_006401.3 oxidoreductase HTATIP2 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15282309 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
10698937 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in import into nucleus IDA
IDA: 通过直接分析推断
15282309 GOA
acts upstream of or within positive regulation of programmed cell death IDA
IDA: 通过直接分析推断
10698937 GOA
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10698937 GOA
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
10698937 GOA
involved in regulation of angiogenesis IDA
IDA: 通过直接分析推断
11313954 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15282309 GOA
located in nuclear envelope IDA
IDA: 通过直接分析推断
15282309 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HTATIP2 蛋白结构

NAD_binding_10

NAD_binding_10: NAD(P)H-binding (22 - 211)

  • 0
  • 100
  • 200
  • 242 a.a.
蛋白主名 其他名称

oxidoreductase HTATIP2

30 kDa HIV-1 TAT-interacting protein

关联疾病

疾病名称 别名
Cervical Cancer

Cervical Cancer, Somatic

Neoplasm Of Uterine Cervix

Cervix Cancer

Uterine Cervical Neoplasm

Cervical Neoplasm

Cervix Uteri Cancer

Tumor Of The Cervix Uteri

CERCA

Uterine Cervical Cancer

Neoplasms Cervical

Uterine Cervical Neoplasms

Cervical Cancers

Cancer, Cervical, Somatic

Malignant Tumor Of Cervix

Cervix Carcinoma
Gnathodiaphyseal Dysplasia

GDD

Osteogenesis Imperfecta With Unusual Skeletal Lesions

Gnathodiaphyseal Sclerosis

Osteogenesis Imperfecta, Levin Type

Levin Syndrome 2

Dysplasia, Gnathodiaphyseal
Gallbladder Adenocarcinoma

Adenocarcinoma Of The Gallbladder

Carcinoma Of The Gallbladder
Small Cell Cancer Of The Lung

Small Cell Lung Cancer

Small Cell Lung Carcinoma

Sclc

Small-Cell Cancer Of Lung

Lung Small Cell Carcinoma

Sclc1

Sccl

Cancer, Lung, Small Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06453 HTATIP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus HTATIP2 VGNC VGNC:62854
Mus musculus HTATIP2 MGD MGI:1859271
Canis familiaris HTATIP2 VGNC VGNC:41821
Rattus norvegicus HTATIP2 RGD RGD:1309941
Bos taurus HTATIP2 VGNC VGNC:29989
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z