1. Gene
  2. IFI44 - interferon induced protein 44 Gene

IFI44 - interferon induced protein 44 Gene

中文名称:干扰素诱导蛋白 44

种属: Homo sapiens

同用名: p44; TLDC5; MTAP44

基因 ID: 10561 | 基因类型: protein coding

关于 IFI44

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,649,789-78,664,078 (from NCBI)

This gene has 9 transcripts (splice variants), 1023 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 19.2), spleen (RPKM 17.3) and 24 other tissues.

功能概要

预计参与免疫反应。预计在对细菌的反应上游或反应内起作用。预计位于细胞质中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in immune response. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

IFI44 基因产物(1)

mRNA Protein Name
NM_006417.5 NP_006408.3 interferon-induced protein 44
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IFI44 蛋白结构

TLD

TLD: TLD (26 - 151)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 444 a.a.
蛋白主名 其他名称

interferon-induced protein 44

TBC/LysM-associated domain containing 5

关联疾病

疾病名称 别名
Multisystem Inflammatory Syndrome In Children

Mis-C

Multisystem Inflammatory Disorder In Children And Adolescents

Paediatric Inflammatory Multisystemic Syndrome

Mic

Hepatitis D

Delta Hepatitis

Hepatitis Delta

Hdv

Hepatitis D Virus

Hepatitis D Infection

Potocki-Shaffer Syndrome

Proximal 11p Deletion Syndrome

Chromosome 11p11.2 Deletion Syndrome

Pss

11p11.2 Deletion

P11pds

Defect11 Syndrome

Deletion Of Chromosome 11p11.2

POSHS

Limited Scleroderma

Limited Cutaneous Systemic Sclerosis

Limited Systemic Sclerosis

Systemic Sclerosis Sine Scleroderma

Crest Syndrome

Limited Cutaneous Systemic Scleroderma

Scleroderma, Limited

Systemic Sclerosis, Limited

Progressive Systemic Sclerosis Sine Scleroderma

Scleroderma, Sine

Crest - [Calcinosis, Raynaud Phenomenon, Oesophageal Dysmotility, Sclerodactyly, And Telangiectasia] Syndrome

Crst - [Calcinosis, Raynaud Phenomenon, Sclerodactyly And Telangiectasia] Syndrome

Aicardi-Goutieres Syndrome

Aicardi Goutieres Syndrome

Cree Encephalitis

Aicardi-Goutières Syndrome

Encephalopathy With Basal Ganglia Calcification

Ags

Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

Pseudotoxoplasmosis Syndrome

Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

Aicardi-Goutieres Syndrome 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus IFI44 VGNC VGNC:30045
Rattus norvegicus IFI44 RGD RGD:1310523
Macaca mulatta IFI44 VGNC VGNC:73400
Felis catus IFI44 VGNC VGNC:62873
Mus musculus IFI44 MGD MGI:2443016
Canis familiaris IFI44 VGNC VGNC:41873