NUDC - nuclear distribution C, dynein complex regulator Gene

中文名称：核分布 C、动力蛋白复合物调节因子

种属: Homo sapiens

同用名: HNUDC; MNUDC; NPD011

基因 ID: 10726 | 基因类型: protein coding

关于 NUDC

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:26,900,161-26,946,871 (from NCBI)

This gene has 4 transcripts (splice variants), 212 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 27.7), adrenal (RPKM 27.5) and 25 other tissues.

功能概要

该基因编码在有丝分裂和胞质分裂中起重要作用的核分布蛋白。编码的蛋白质参与有丝分裂期间的纺锤体形成和胞质分裂期间的微管组织。在 2 号染色体上发现了该基因的假基因。[RefSeq 提供，2012 年 2 月]

This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]

NUDC 基因产物(1)

mRNA	Protein	Name
NM_006600.4	NP_006591.1	nuclear migration protein nudC

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	22159412	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in mitotic metaphase chromosome alignment	IMP IMP: 通过突变表型推断	25789526	GOA
involved in mitotic spindle organization	IMP IMP: 通过突变表型推断	25789526	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	25468996	GOA
located in midbody	IDA IDA: 通过直接分析推断	25789526	GOA
located in mitotic spindle	IDA IDA: 通过直接分析推断	25789526	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NUDC 蛋白结构

Nudc_N

0
100
200
300
331 a.a.

蛋白主名

其他名称

nuclear migration protein nudC

nuclear distribution C homolog

NUDC 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	NUDC	Q9Y266	ATN1	Homo sapiens	Q86V38	Validated Y2H	32814053
种属内	NUDC	Q9Y266	ATN1	Homo sapiens	Q86V38	Y2H Array	32814053
种属内	NUDC	Q9Y266	ATN1	Homo sapiens	Q86V38	Y2H Pooling	32814053
种属内	NUDC	Q9Y266	DYNC2I1	Homo sapiens	Q8WVS4	TAP	27173435
种属内	NUDC	Q9Y266	POC1A	Homo sapiens	Q8NBT0	Lumier	25036637
种属内	NUDC	Q9Y266	GIPC1	Homo sapiens	O14908-2	Y2H Array	32814053
种属内	NUDC	Q9Y266	GIPC1	Homo sapiens	O14908-2	Y2H Pooling	32814053
种属内	NUDC	Q9Y266	GIPC1	Homo sapiens	O14908-2	Validated Y2H	32814053
种属内	NUDC	Q9Y266	DNAJA2	Homo sapiens	O60884	Lumier	25036637
种属内	NUDC	Q9Y266	DNAJA2	Homo sapiens	O60884	Anti Tag CoIP	25036637
种属内	NUDC	Q9Y266	EML1	Homo sapiens	O00423	Lumier	25036637

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 NUDC 蛋白

目录号	产品名	蛋白编号	纯度
HY-P75947	NUDC Protein, Human (HEK293, His)	Q9Y266 (M1-N331)	≥95%

NUDC 抗体

目录号	产品名	应用	反应物种
HY-P82626	NUDC Antibody (YA2371)	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

关联疾病

疾病名称

别名

Body Mass Index Quantitative Trait Locus 11

OBESITY	Obesity, Susceptibility To
Leanness, Inherited	Obesity, Susceptibility To, Bmiq11
Obesity, Mild, Early-Onset	Obesity, Association With
Obesity, Early-Onset, Susceptibility To	Obesity, Severe
Obesity, Severe, And Type Ii Diabetes	Obesity, Late-Onset
Obesity , Susceptibility To	BMIQ11
Obesity Bmiq11	Obesity, Early-Onset
Simple Obesity Nos	Excess Fat
Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified	Adiposis

Lissencephaly

Pachygyria	Broad Gyri Of Cerebrum
Large Gyri Of Cerebrum	Macrogyria

3mc Syndrome 1

Oculopalatoskeletal Syndrome	3MC1
Craniosynostosis With Lid Anomalies	Michels Syndrome, Formerly
Michels Syndrome	3mc Syndrome, Type 1

Hermansky-Pudlak Syndrome 3

HPS3	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial
Delta Storage Pool Disease	Hermansky-Pudlak Syndrome, Type 3
Platelet Storage Pool Deficiency	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Lissencephaly 1

LIS1	Classic Lissencephaly
Ils	Subcortical Laminar Heterotopia
Lissencephaly Due To Lis1 Mutation	Lissencephaly Sequence, Isolated
Lissencephaly, Classic	Pafah1b1-Related Lissencephaly
Classical Lissencephaly	Lissencephaly Type 1
Lissencephaly-1	Subcortical Band Heterotopia
Double Cortex	Lissencephaly Classic
Lissencephaly Sequence Isolated	Isolated Lissencephaly Sequence
Type 1 Lissencephaly	Lissencephaly Syndrome Type 1
SBH	Sclh
Lissencephaly, Type 1	Type I Lissencephaly

Miller-Dieker Lissencephaly Syndrome

Miller-Dieker Syndrome	Mds
MDLS	Miller Dieker Syndrome
Classical Lissencephaly Syndrome	Lissencephaly Due To 17p13.3 Deletion
Monosomy 17p13.3	Telomeric Deletion 17p
Classical Lissencephaly

Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia	ALL
Acute Lymphocytic Leukemia	Leukemia, Acute Lymphocytic, Susceptibility To, 1
Acute Lymphoblastic Leukaemia	Precursor Lymphoblastic Lymphoma/Leukemia
Precursor Lymphoid Neoplasm	Leukemia, Acute Lymphoblastic, Susceptibility To
B-Cell Acute Lymphoblastic Leukemia	Leukemia, Acute Lymphocytic 1
Acute Lymphocytic Leukaemia	Acute Lymphoblastic Leukemia/Lymphoma
All1	Childhood Acute Lymphoblastic Leukemia
Leukemia Acute Lymphoblastic 1	Leukemia Acute Lymphoblastic B-Hyperdiploid
Leukemia Acute Lymphocytic	Leukemia Acute Lymphocytic 1
Leukemia B-Cell Acute Lymphoblastic	Leukemia T-Cell Acute Lymphoblastic
Leukemia, Acute Lymphoblastic, 3	ALL3
Lymphoblastic Leukemia Acute	Leukemia, Acute, Lymphoblastic
Precursor Cell Lymphoblastic Leukemia Lymphoma	Leukemia, Lymphocytic, Acute, L1
Leukemia, Acute Lymphoblastic, Susceptibility To, 3

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS09657	NUDC Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	NUDC	VGNC	VGNC:68588
Macaca mulatta	NUDC	VGNC	VGNC:100021
Mus musculus	NUDC	MGD	MGI:106014
Rattus norvegicus	NUDC	RGD	RGD:3215
Canis familiaris	NUDC	VGNC	VGNC:44021
Bos taurus	NUDC	VGNC	VGNC:32321
Others	NUDC	NCBI

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上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

NUDC - nuclear distribution C, dynein complex regulator Gene

关于 NUDC

功能概要

NUDC 基因产物(1)

NUDC 蛋白结构

NUDC 蛋白互作信息

重组 NUDC 蛋白

NUDC 抗体

关联疾病

直系同源

热门区域

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NUDC - nuclear distribution C, dynein complex regulator Gene

关于 NUDC

功能概要

NUDC 基因产物(1)

NUDC 蛋白结构

NUDC 蛋白互作信息

重组 NUDC 蛋白

NUDC 抗体

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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Z