DYNC2I1 - dynein 2 intermediate chain 1 Gene

种属: Homo sapiens (human)

同用名: DIC6; SRPS6; SRTD8; WDR60; FAP163; CFAP163

关于 DYNC2I1

功能概要

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 Amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, Apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014]