2. Gene
  3. DYNC2I2 - dynein 2 intermediate chain 2 Gene

DYNC2I2 - dynein 2 intermediate chain 2 Gene

  • 基因
  • 蛋白
  • 相关产品

种属: Homo sapiens (human)

同用名: DIC5; WDR34; FAP133; SRTD11; CFAP133; bA216B9.3

基因 ID: 89891 | 基因类型: protein coding

关于 DYNC2I2

功能概要

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 Amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, Apoptosis, and gene regulation. Defects in this gene are a cause of short-rib thoracic dysplasia 11 with or without polydactyly. [provided by RefSeq, Mar 2014]

DYNC2I2 基因产物(1)

mRNA Protein Name
XM_011519179.3 XP_011517481.1 cytoplasmic dynein 2 intermediate chain 2 isoform X2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dynein light chain binding IPI
IPI: 通过物理相互作用推断
25830415 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cilium assembly IGI
IGI: 通过遗传相互作用推断
25205765 GOA
involved in intraciliary retrograde transport IMP
IMP: 通过突变表型推断
29742051 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
25205765 GOA
located in ciliary basal body IDA
IDA: 通过直接分析推断
25205765 GOA
located in cilium IDA
IDA: 通过直接分析推断
25205765 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
25205765 GOA
part of cytoplasmic dynein complex IDA
IDA: 通过直接分析推断
25205765 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytoplasmic dynein 2 intermediate chain 2

WD repeat domain 34

WD repeat-containing protein 34

DYNC2I2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra DYNC2I2 Q96EX3 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra DYNC2I2 Q96EX3 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra DYNC2I2 Q96EX3 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
25416956
Intra DYNC2I2 Q96EX3 TRIM54 Homo sapiens Q9BYV2
Y2H Array
25416956
Intra DYNC2I2 Q96EX3 DYNC2I1 Homo sapiens Q8WVS4
TAP
27173435
Intra DYNC2I2 Q96EX3 COIL Homo sapiens P38432
Y2H Array
25416956
Intra DYNC2I2 Q96EX3 COIL Homo sapiens P38432
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04084 DYNC1I2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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