Grm6 - glutamate receptor, metabotropic 6 Gene

中文名称：谷氨酸受体，代谢型 6

种属: Mus musculus

同用名: Gm3; nob2; nob3; nob4; nerg1; Gprc1f; mGluR6

关于 Grm6

功能概要

预计该基因编码的蛋白能使腺苷酸环化酶抑制 G 蛋白偶联的谷氨酸受体活性和蛋白质同源二聚化活性。参与光刺激的运动行为和感官知觉。在相机型眼睛和信号转导中作用于视网膜发育的上游或内部。位于新生长的细胞尖端。在前列腺中表达；视网膜内核层；和睾丸。用于研究先天性静止性夜盲症 1B。该基因的人类直系同源物与先天性静止性夜盲症 1B 相关。与人类 GRM6（谷氨酸代谢受体 6）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Adenylate Cyclase inhibiting G protein-coupled glutamate receptor activity and protein homodimerization activity. Involved in locomotory behavior and sensory perception of light stimulus. Acts upstream of or within retina development in camera-type eye and signal transduction. Located in new growing cell tip. Is expressed in prostate gland; retina inner nuclear layer; and testis. Used to study congenital stationary night blindness 1B. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1B. Orthologous to human GRM6 (glutamate metabotropic receptor 6). [provided by Alliance of Genome Resources, Apr 2022]