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  2. TSPAN9 - tetraspanin 9 Gene

TSPAN9 - tetraspanin 9 Gene

中文名称:四跨膜蛋白 9

种属: Homo sapiens

同用名: NET5; NET-5; PP1057

基因 ID: 10867 | 基因类型: protein coding

关于 TSPAN9

Cytogenetic location: 12p13.33-p13.32 Genomic coordinates (GRCh38): 12:3,077,379-3,286,559 (from NCBI)

This gene has 9 transcripts (splice variants), 271 orthologues and 32 paralogues. Broad expression in heart (RPKM 31.5), placenta (RPKM 20.4) and 23 other tissues.

功能概要

由该基因编码的蛋白质是跨膜 4 超家族的成员,也称为四跨膜蛋白家族。这些成员中的大多数是细胞表面蛋白,其特征在于存在四个疏水结构域。这些蛋白质介导在细胞发育、活化、生长和运动的调节中起作用的信号转导事件。已经鉴定出编码相同蛋白质的可变剪接转录本。[RefSeq 提供,2009 年 11 月]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]

TSPAN9 基因产物(2)

mRNA Protein Name
NM_001168320.2 NP_001161792.1 tetraspanin-9
NM_006675.5 NP_006666.1 tetraspanin-9
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
18795891 GOA
located in tetraspanin-enriched microdomain IDA
IDA: 通过直接分析推断
18795891 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TSPAN9 蛋白结构

Tetraspannin

Tetraspannin: Tetraspanin family (8 - 230)

  • 0
  • 100
  • 200
  • 239 a.a.
蛋白主名 其他名称

tetraspanin-9

new EST tetraspan 5

关联疾病

疾病名称 别名
Fallopian Tube Carcinoma

Fallopian Tube Cancer

Cancer Of The Fallopian Tube

Carcinoma Of Fallopian Tube

Neoplasm Of Fallopian Tube

Fallopian Tube Neoplasms

Fallopian Tube Ca

Fallopian Tube Neoplasm

Malignant Neoplasm Of Uterine Tube

Malignant Tumor Of Fallopian Tube

Malignant Tumour Of Fallopian Tube

Tumor Of The Fallopian Tube

Tumor, Fallopian Tube, Malignant

Malignant Tumor Of Fallopian Tubes

Cancer Of Fallopian Tubes

Malignant Tubal Tumor

Tubal Cancer

Malignant Neoplasm Of Fallopian Tube

Primary Malignant Neoplasm Of Fallopian Tube

Cancer Of The Oviduct

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta TSPAN9 VGNC VGNC:100115
Felis catus TSPAN9 VGNC VGNC:66637
Canis familiaris TSPAN9 VGNC VGNC:47926
Mus musculus TSPAN9 MGD MGI:1924558
Rattus norvegicus TSPAN9 RGD RGD:1304740
Bos taurus TSPAN9 VGNC VGNC:36443