USP19 - ubiquitin specific peptidase 19 Gene

中文名称：泛素特异性肽酶 19

种属: Homo sapiens

同用名: ZMYND9

关于 USP19

功能概要

蛋白质泛素化控制许多细胞内过程，包括细胞周期进程、转录激活和信号转导。这个动态过程涉及泛素结合酶和去泛素化酶，添加和去除泛素。去泛素化酶是半胱氨酸蛋白酶，可特异性地从泛素缀合的蛋白质底物上切割泛素。这种蛋白质是一种泛素蛋白连接酶，在肌肉萎缩中发挥作用。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2017 年 5 月]

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating Enzymes and deubiquitinating Enzymes, adds and removes ubiquitin. Deubiquitinating Enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein Ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]